No, it's not possible because:
First of all, you can't upload files to a lua bios
Second of all, ISO files are just disk copies, you don't boot from them. You flash them, then you boot it from the storage device.
Third of all, how are you expecting a minecraft mod to support actual ISO files/actual operating systems?
And last, opencomputers runs on lua. If you had a bootable operating system on a ISO, it's not gonna work on a minecraft mod.
Also, the max size for OC HDD's is like 8096 kb or something, so sadly it's not possible.
Cool idea tho.
-TrueDuck